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2-BFI hydrochloride

CAS No. 89196-95-2

2-BFI hydrochloride ( —— )

Catalog No. M27593 CAS No. 89196-95-2

2-BFI hydrochloride is a high-affinity agonist of I2-imidazoline receptor. 2-BFI hydrochloride can be used in studies about protection against stroke and acute inflammatory immune disease.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    2-BFI hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    2-BFI hydrochloride is a high-affinity agonist of I2-imidazoline receptor. 2-BFI hydrochloride can be used in studies about protection against stroke and acute inflammatory immune disease.
  • Description
    2-BFI hydrochloride is a high-affinity agonist of I2-imidazoline receptor. 2-BFI hydrochloride can be used in studies about protection against stroke and acute inflammatory immune disease.(In Vivo):2-BFI hydrochloride administration after dMCAO improved the neurological deficits and decreased the infarct volume. 2-BFI hydrochloride reduced phosphorylation of mTOR and p70S6, increased IL-10 and TGF-β, and decreased IFN-γ levels in ischemic rats. 2-BFI hydrochloride attenuates ischemic injury by inhibiting the activation of mTOR signaling and modulating neuroinflammation after stroke in rats.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    BRM/BRG1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    89196-95-2
  • Formula Weight
    222.7
  • Molecular Formula
    C11H11ClN2O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cl.N1=C(NCC1)C=2OC=3C=CC=CC3C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Centore, Richard C. et al. Preparation of BRG1/BRM inhibitors for treating cancer. US20220079940 A1.
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