2-BFI hydrochloride ( —— )

Catalog No. M27593 CAS No. 89196-95-2

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Product Name

2-BFI hydrochloride
Note

Research use only, not for human use.
Brief Description

2-BFI hydrochloride is a high-affinity agonist of I2-imidazoline receptor. 2-BFI hydrochloride can be used in studies about protection against stroke and acute inflammatory immune disease.
Description

2-BFI hydrochloride is a high-affinity agonist of I2-imidazoline receptor. 2-BFI hydrochloride can be used in studies about protection against stroke and acute inflammatory immune disease.(In Vivo):2-BFI hydrochloride administration after dMCAO improved the neurological deficits and decreased the infarct volume. 2-BFI hydrochloride reduced phosphorylation of mTOR and p70S6, increased IL-10 and TGF-β, and decreased IFN-γ levels in ischemic rats. 2-BFI hydrochloride attenuates ischemic injury by inhibiting the activation of mTOR signaling and modulating neuroinflammation after stroke in rats.
Synonyms

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Pathway

Others
Target

Other Targets
Recptor

BRM/BRG1
Research Area

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Indication

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1.Centore, Richard C. et al. Preparation of BRG1/BRM inhibitors for treating cancer. US20220079940 A1.

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